We found that pancreatic cancers contain an average of 63 genetic alterations, the majority of which are point mutations.

我们发现胰腺癌平均含有63个基因的改变，大多数为点突变。

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Objective To detect genetic alterations in pleomorphic xanthoastrocytoma (PXA), and to investigate the mechanism of development of this neoplasm.

目的研究多形性黄色星形细胞瘤（PXA）的遗传学异常，以探讨该肿瘤的发病机制。

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Scientists know that UV light can cause genetic alterations that prevent DNA from replicating properly, and these mutations can lead to diseases such as cancer.

科学家认为紫外光能导致基因改变阻止DNA正常复制并且形成突变导致疾病例如癌症。

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Targeting genetic alterations can provide a basis for Specificity, but cannot generally provide Comprehensiveness.

FORBES: Cancer's New Era Of Promise And Chaos

Drug resistance and disease progression have been observed all for anticancer drugs that target specific genetic alterations.

FORBES: Cancer's New Era Of Promise And Chaos

But for 1% who carry a significant number of genetic alterations, the risk rises to one in two.

BBC: DNA test reveals 80 markers for inherited cancer risk